SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00865

Signal sequence   MKKLLLILLLLLLLLAVGASAAQ

Length  23

Organism  Artificial

UniProt ID  NA,

Motif  1..23



Activity Information


Pathway  NA

Natural/Artificial  Artificial

Subcellular location  Extracellular environment

Secretion efficiency  NA

Type  NA



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB00865.cif

Structure  SPKB00865.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2419.17744

Aliphatic index  233.4782609

Isoelectric point  10.80537956

Charge (pH=7)   1.997394232

Topological polar surface area  818.88

Aromaticity  0

Average rotatable bonds  3.695652174

Number of hydrogen bond donors  28

Number of hydrogen bond acceptors  29

X logP energy  0.253

Hydropathy 



Literature Information


Title  SYNTHETIC PRE-PROTEIN SIGNAL PEPTIDES FOR DIRECTING SECRETION OF HETEROLOGOUS PROTEINS IN BACILLUS BACTERIA

DOI  NA,

Publication Year  2024

PubMed ID  NA,

Patent ID  US20240166694A1,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.