SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00864

Signal sequence   MKKKLLLALLLSLALLLSLAASAASAA

Length  27

Organism  Artificial

UniProt ID  NA,

Motif  1..27



Activity Information


Pathway  NA

Natural/Artificial  Artificial

Subcellular location  Extracellular environment

Secretion efficiency  NA

Type  NA



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB00864.cif

Structure  SPKB00864.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2695.42674

Aliphatic index  188.5185185

Isoelectric point  11.10307074

Charge (pH=7)   2.997099198

Topological polar surface area  978.9

Aromaticity  0

Average rotatable bonds  3.481481481

Number of hydrogen bond donors  35

Number of hydrogen bond acceptors  36

X logP energy  -5.2213

Hydropathy 



Literature Information


Title  SYNTHETIC PRE-PROTEIN SIGNAL PEPTIDES FOR DIRECTING SECRETION OF HETEROLOGOUS PROTEINS IN BACILLUS BACTERIA

DOI  NA,

Publication Year  2024

PubMed ID  NA,

Patent ID  US20240166694A1,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.