SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00862

Signal sequence   MKLFFVGIVTTLLTLVSC

Length  18

Organism  Komagataella pastoris?

UniProt ID  NA,

Motif  1..18



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB00862.cif

Structure  SPKB00862.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1985.51414

Aliphatic index  156.6666667

Isoelectric point  8.545189979

Charge (pH=7)   0.93571455

Topological polar surface area  664.96

Aromaticity  0.111111111

Average rotatable bonds  3.555555556

Number of hydrogen bond donors  25

Number of hydrogen bond acceptors  26

X logP energy  -2.0982

Hydropathy 



Literature Information


Title  SIGNAL PEPTIDES FOR INCREASED PROTEIN SECRETION

DOI  NA,

Publication Year  2024

PubMed ID  NA,

Patent ID  US20240141363A1,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.