SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00859

Signal sequence   RSGVKWTWIFLTMALTMAMAT

Length  21

Organism  Artificial

UniProt ID  NA,

Motif  1..21



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB00859.cif

Structure  SPKB00859.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2415.95534

Aliphatic index  83.80952381

Isoelectric point  11.65177567

Charge (pH=7)   1.997685954

Topological polar surface area  865.97

Aromaticity  0.142857143

Average rotatable bonds  3.619047619

Number of hydrogen bond donors  33

Number of hydrogen bond acceptors  32

X logP energy  -4.56253

Hydropathy 



Literature Information


Title  FLAVIVIRUS SIGNAL PEPTIDES, VACCINE CONSTRUCTS, AND METHODS THEREFOR

DOI  NA,

Publication Year  2023

PubMed ID  NA,

Patent ID  US20230272405A1,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.