SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00854

Signal sequence   RSGVPWTWIFLTMALTMAMAT

Length  21

Organism  Artificial

UniProt ID  NA,

Motif  1..21



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB00854.cif

Structure  SPKB00854.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2384.89794

Aliphatic index  83.80952381

Isoelectric point  10.55000222

Charge (pH=7)   0.997980988

Topological polar surface area  831.16

Aromaticity  0.142857143

Average rotatable bonds  3.380952381

Number of hydrogen bond donors  31

Number of hydrogen bond acceptors  31

X logP energy  -4.18533

Hydropathy 



Literature Information


Title  FLAVIVIRUS SIGNAL PEPTIDES, VACCINE CONSTRUCTS, AND METHODS THEREFOR

DOI  NA,

Publication Year  2023

PubMed ID  NA,

Patent ID  US20230272405A1,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.