SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00846

Signal sequence   MRSGVKWTWIFLTMALTMAMAT

Length  22

Organism  Artificial

UniProt ID  NA,

Motif  1..22



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB00846.cif

Structure  SPKB00846.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2547.14794

Aliphatic index  80

Isoelectric point  11.65177567

Charge (pH=7)   1.997685954

Topological polar surface area  895.07

Aromaticity  0.136363636

Average rotatable bonds  3.681818182

Number of hydrogen bond donors  34

Number of hydrogen bond acceptors  34

X logP energy  -4.32463

Hydropathy 



Literature Information


Title  FLAVIVIRUS SIGNAL PEPTIDES, VACCINE CONSTRUCTS, AND METHODS THEREFOR

DOI  NA,

Publication Year  2023

PubMed ID  NA,

Patent ID  US20230272405A1,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.