SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00845

Signal sequence   MRSGVRWTWIFLTMALTMAMAT

Length  22

Organism  Artificial

UniProt ID  NA,

Motif  1..22



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB00845.cif

Structure  SPKB00845.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2575.16134

Aliphatic index  80

Isoelectric point  12.50010931

Charge (pH=7)   1.997977677

Topological polar surface area  930.95

Aromaticity  0.136363636

Average rotatable bonds  3.681818182

Number of hydrogen bond donors  36

Number of hydrogen bond acceptors  34

X logP energy  -5.19036

Hydropathy 



Literature Information


Title  FLAVIVIRUS SIGNAL PEPTIDES, VACCINE CONSTRUCTS, AND METHODS THEREFOR

DOI  NA,

Publication Year  2023

PubMed ID  NA,

Patent ID  US20230272405A1,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.