SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00837

Signal sequence   MRSGVMWTWIFLTMALTMAMAT

Length  22

Organism  Artificial

UniProt ID  NA,

Motif  1..22



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB00837.cif

Structure  SPKB00837.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2550.16644

Aliphatic index  80

Isoelectric point  10.55000222

Charge (pH=7)   0.997980988

Topological polar surface area  869.05

Aromaticity  0.136363636

Average rotatable bonds  3.636363636

Number of hydrogen bond donors  33

Number of hydrogen bond acceptors  34

X logP energy  -3.70053

Hydropathy 



Literature Information


Title  FLAVIVIRUS SIGNAL PEPTIDES, VACCINE CONSTRUCTS, AND METHODS THEREFOR

DOI  NA,

Publication Year  2023

PubMed ID  NA,

Patent ID  US20230272405A1,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.