SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00833

Signal sequence   MRSGVDWTWIFLTMALTMAMAT

Length  22

Organism  Artificial

UniProt ID  NA,

Motif  1..22



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB00833.cif

Structure  SPKB00833.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2534.06244

Aliphatic index  80

Isoelectric point  6.338718596

Charge (pH=7)   -0.001572528

Topological polar surface area  906.35

Aromaticity  0.136363636

Average rotatable bonds  3.590909091

Number of hydrogen bond donors  34

Number of hydrogen bond acceptors  34

X logP energy  -4.97893

Hydropathy 



Literature Information


Title  FLAVIVIRUS SIGNAL PEPTIDES, VACCINE CONSTRUCTS, AND METHODS THEREFOR

DOI  NA,

Publication Year  2023

PubMed ID  NA,

Patent ID  US20230272405A1,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.