SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00832

Signal sequence   MGGNEGSIMWLASLAVVIACAGA

Length  23

Organism  Artificial

UniProt ID  NA,

Motif  1..23



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB00832.cif

Structure  SPKB00832.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2221.63254

Aliphatic index  114.7826087

Isoelectric point  3.849962145

Charge (pH=7)   -1.062215294

Topological polar surface area  840.16

Aromaticity  0.043478261

Average rotatable bonds  3.086956522

Number of hydrogen bond donors  30

Number of hydrogen bond acceptors  31

X logP energy  -7.9298

Hydropathy 



Literature Information


Title  FLAVIVIRUS SIGNAL PEPTIDES, VACCINE CONSTRUCTS, AND METHODS THEREFOR

DOI  NA,

Publication Year  2023

PubMed ID  NA,

Patent ID  US20230272405A1,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.