SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00825

Signal sequence   GAVTSVGIVGLLLTTAMA

Length  18

Organism  Artificial

UniProt ID  NA,

Motif  1..18



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB00825.cif

Structure  SPKB00825.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1674.02884

Aliphatic index  151.6666667

Isoelectric point  6.099999998

Charge (pH=7)   -0.002015701

Topological polar surface area  638.94

Aromaticity  0

Average rotatable bonds  2.944444444

Number of hydrogen bond donors  23

Number of hydrogen bond acceptors  24

X logP energy  -6.366

Hydropathy 



Literature Information


Title  FLAVIVIRUS SIGNAL PEPTIDES, VACCINE CONSTRUCTS, AND METHODS THEREFOR

DOI  NA,

Publication Year  2023

PubMed ID  NA,

Patent ID  US20230272405A1,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.