SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00824

Signal sequence   GAHTSVGIVGLLLTTAMA

Length  18

Organism  Artificial

UniProt ID  NA,

Motif  1..18



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB00824.cif

Structure  SPKB00824.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1712.03734

Aliphatic index  135.5555556

Isoelectric point  7.550323994

Charge (pH=7)   0.08889339

Topological polar surface area  667.62

Aromaticity  0

Average rotatable bonds  3

Number of hydrogen bond donors  24

Number of hydrogen bond acceptors  25

X logP energy  -7.0562

Hydropathy 



Literature Information


Title  FLAVIVIRUS SIGNAL PEPTIDES, VACCINE CONSTRUCTS, AND METHODS THEREFOR

DOI  NA,

Publication Year  2023

PubMed ID  NA,

Patent ID  US20230272405A1,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.