SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00818

Signal sequence   MGAKTSVGIVGLLLTTAMA

Length  19

Organism  Artificial

UniProt ID  NA,

Motif  1..19



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB00818.cif

Structure  SPKB00818.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1834.26294

Aliphatic index  128.4210526

Isoelectric point  9.700002532

Charge (pH=7)   0.997689266

Topological polar surface area  694.06

Aromaticity  0

Average rotatable bonds  3.210526316

Number of hydrogen bond donors  25

Number of hydrogen bond acceptors  27

X logP energy  -6.6551

Hydropathy 



Literature Information


Title  FLAVIVIRUS SIGNAL PEPTIDES, VACCINE CONSTRUCTS, AND METHODS THEREFOR

DOI  NA,

Publication Year  2023

PubMed ID  NA,

Patent ID  US20230272405A1,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.