SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00803

Signal sequence   MPLLLWVLLLWAGALAEVQLVESGGG

Length  26

Organism  Artificial

UniProt ID  NA,

Motif  1..26



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB00803.cif

Structure  SPKB00803.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2736.30784

Aliphatic index  165

Isoelectric point  3.613691326

Charge (pH=7)   -1.998465455

Topological polar surface area  951.53

Aromaticity  0.076923077

Average rotatable bonds  3.307692308

Number of hydrogen bond donors  32

Number of hydrogen bond acceptors  32

X logP energy  -1.8649

Hydropathy 



Literature Information


Title  CHIMERIC SIGNAL PEPTIDES FOR PROTEIN PRODUCTION

DOI  NA,

Publication Year  2021

PubMed ID  NA,

Patent ID  US20210388046A1,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.