SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00802

Signal sequence   MRVPAQLLGLLLLWLPGARC

Length  20

Organism  Artificial

UniProt ID  NA,

Motif  1..20



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  7WUE,

Predicted Structure ID  SPKB00802.cif

Structure  SPKB00802.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2220.80874

Aliphatic index  161

Isoelectric point  10.52640717

Charge (pH=7)   1.936002961

Topological polar surface area  781.32

Aromaticity  0.05

Average rotatable bonds  3.45

Number of hydrogen bond donors  28

Number of hydrogen bond acceptors  26

X logP energy  -1.89786

Hydropathy 



Literature Information


Title  CHIMERIC SIGNAL PEPTIDES FOR PROTEIN PRODUCTION

DOI  NA,

Publication Year  2021

PubMed ID  NA,

Patent ID  US20210388046A1,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.