SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00795

Signal sequence   METDTLLLLLPLLWVPGSTG

Length  20

Organism  Artificial

UniProt ID  NA,

Motif  1..20



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB00795.cif

Structure  SPKB00795.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2169.60424

Aliphatic index  151

Isoelectric point  3.550073557

Charge (pH=7)   -1.999794094

Topological polar surface area  769.95

Aromaticity  0.05

Average rotatable bonds  3.3

Number of hydrogen bond donors  26

Number of hydrogen bond acceptors  28

X logP energy  -3.1853

Hydropathy 



Literature Information


Title  CHIMERIC SIGNAL PEPTIDES FOR PROTEIN PRODUCTION

DOI  NA,

Publication Year  2021

PubMed ID  NA,

Patent ID  US20210388046A1,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.