SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00793

Signal sequence   MLGIWTLLPLVLTSVARLSSKSVNA

Length  25

Organism  Homo sapiens (Human)

UniProt ID  P25445,

Motif  1..25



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB00793.cif

Structure  SPKB00793.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2670.24924

Aliphatic index  152

Isoelectric point  11.65177567

Charge (pH=7)   1.997685954

Topological polar surface area  1021.11

Aromaticity  0.04

Average rotatable bonds  3.44

Number of hydrogen bond donors  37

Number of hydrogen bond acceptors  36

X logP energy  -8.02283

Hydropathy 



Literature Information


Title  Artificial signal peptide

DOI  NA,

Publication Year  2018

PubMed ID  NA,

Patent ID  US9908928B2,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.