SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00757

Signal sequence   MAE

Length  3

Organism  Artificial

UniProt ID  NA,

Motif  1..3



Activity Information


Pathway  Sec

Natural/Artificial  Artificial

Subcellular location  Periplasmic space

Secretion efficiency  NA

Type  NA



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB00757.cif

Structure  SPKB00757.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  349.40214

Aliphatic index  33.33333333

Isoelectric point  3.849983241

Charge (pH=7)   -1.000240578

Topological polar surface area  158.82

Aromaticity  0

Average rotatable bonds  3.666666667

Number of hydrogen bond donors  5

Number of hydrogen bond acceptors  6

X logP energy  -0.9943

Hydropathy 



Literature Information


Title  Artificial signal peptide for expressing an insoluble protein as a soluble active form

DOI  NA,

Publication Year  2016

PubMed ID  NA,

Patent ID  US9422356B2,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.