General Information
SPKB ID SPKB00744
Signal sequence MWQLLLPTALLLLVSAGMRT
Length 20
Organism Homo sapiens (Human)
UniProt ID A0A8V8TQ03,
Motif 1..20
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID 5D6D,
Predicted Structure ID SPKB00744.cif
Physicochemical Information
Molecular weight 2227.79484
Aliphatic index 161
Isoelectric point 10.55000222
Charge (pH=7) 0.997980988
Topological polar surface area 788.9
Aromaticity 0.05
Average rotatable bonds 3.55
Number of hydrogen bond donors 28
Number of hydrogen bond acceptors 28
X logP energy -2.72153
Hydropathy
Literature Information
Title Heterologous intron within a signal peptide
DOI NA,
Publication Year 2016
PubMed ID NA,
Patent ID US9249201B2,