SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00733

Signal sequence   MAWVWTLLFLMAAAQSAQA

Length  19

Organism  Artificial

UniProt ID  NA,

Motif  1..19



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  Increase R593 antibody production by 1.58 times

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB00733.cif

Structure  SPKB00733.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2109.53174

Aliphatic index  108.4210526

Isoelectric point  6.099999998

Charge (pH=7)   -0.002015701

Topological polar surface area  745.34

Aromaticity  0.157894737

Average rotatable bonds  3.368421053

Number of hydrogen bond donors  26

Number of hydrogen bond acceptors  26

X logP energy  -2.8606

Hydropathy 



Literature Information


Title  Signal peptide, and use thereof for producing recombinant proteins

DOI  NA,

Publication Year  2014

PubMed ID  NA,

Patent ID  US8883450B2,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.