SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00732

Signal sequence   MRWSWIFLFLLSITASVHC

Length  19

Organism  Artificial

UniProt ID  NA,

Motif  1..19



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  Increase R593 antibody production by 1.71 times

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB00732.cif

Structure  SPKB00732.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2310.80294

Aliphatic index  123.1578947

Isoelectric point  8.557478416

Charge (pH=7)   1.026915363

Topological polar surface area  790.2

Aromaticity  0.210526316

Average rotatable bonds  3.684210526

Number of hydrogen bond donors  31

Number of hydrogen bond acceptors  28

X logP energy  -1.76583

Hydropathy 



Literature Information


Title  Signal peptide, and use thereof for producing recombinant proteins

DOI  NA,

Publication Year  2014

PubMed ID  NA,

Patent ID  US8883450B2,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.