SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00729

Signal sequence   SSKQKKRGGKTGIAVMIGLIASVGA

Length  25

Organism  Artificial

UniProt ID  NA,

Motif  1..25



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB00729.cif

Structure  SPKB00729.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2457.96084

Aliphatic index  97.6

Isoelectric point  11.99738138

Charge (pH=7)   4.996800853

Topological polar surface area  1051.71

Aromaticity  0

Average rotatable bonds  3.56

Number of hydrogen bond donors  38

Number of hydrogen bond acceptors  37

X logP energy  -13.09783

Hydropathy 



Literature Information


Title  West Nile virus prM-E signal peptide facilitating the efficient assembly, maturation, and release of virus-like particles (VLPs)

DOI  NA,

Publication Year  2014

PubMed ID  NA,

Patent ID  US8795687B2,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.