SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00722

Signal sequence   MTVFFILMMLVAPSMA

Length  16

Organism  Artificial

UniProt ID  NA,

Motif  1..16



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB00722.cif

Structure  SPKB00722.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1802.33984

Aliphatic index  121.875

Isoelectric point  6.099999998

Charge (pH=7)   -0.002015701

Topological polar surface area  531.49

Aromaticity  0.125

Average rotatable bonds  3.5

Number of hydrogen bond donors  18

Number of hydrogen bond acceptors  23

X logP energy  0.5375

Hydropathy 



Literature Information


Title  Recombinant dengue virus antigens comprising the C15 signal peptide, full-length PRM protein, and full-length E protein

DOI  NA,

Publication Year  2012

PubMed ID  NA,

Patent ID  US8158131B2,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.