SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00709

Signal sequence   MKRNRFFNTSAAIAISIALNTFFCSMQTIA

Length  30

Organism  Klebsiella oxytoca

UniProt ID  P08704,

Motif  1..30



Activity Information


Pathway  NA

Natural/Artificial  Natural

Subcellular location  Extracellular environment

Secretion efficiency  Interferon2b: 95mg/L

Type  NA



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB00709.cif

Structure  SPKB00709.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3368.97774

Aliphatic index  81.66666667

Isoelectric point  11.48119255

Charge (pH=7)   2.935707927

Topological polar surface area  1350.78

Aromaticity  0.133333333

Average rotatable bonds  3.7

Number of hydrogen bond donors  49

Number of hydrogen bond acceptors  47

X logP energy  -14.13916

Hydropathy 



Literature Information


Title  Signal peptide for the production of recombinant proteins

DOI  NA,

Publication Year  2012

PubMed ID  NA,

Patent ID  US8148494B2,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.