SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00708

Signal sequence   MKRNRFFNTSAAIAISIALQIFFPSASAFA

Length  30

Organism  Artificial

UniProt ID  NA,

Motif  1..30



Activity Information


Pathway  NA

Natural/Artificial  Artificial

Subcellular location  Extracellular environment

Secretion efficiency  Interferon2b: 156mg/L

Type  NA



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB00708.cif

Structure  SPKB00708.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3291.86144

Aliphatic index  88.33333333

Isoelectric point  12.51647815

Charge (pH=7)   2.997682643

Topological polar surface area  1278.67

Aromaticity  0.166666667

Average rotatable bonds  3.5

Number of hydrogen bond donors  45

Number of hydrogen bond acceptors  43

X logP energy  -11.67806

Hydropathy 



Literature Information


Title  Signal peptide for the production of recombinant proteins

DOI  NA,

Publication Year  2012

PubMed ID  NA,

Patent ID  US8148494B2,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.