General Information
SPKB ID SPKB00705
Signal sequence MYQRMLRCGAELGSPGGGGGGGGGGGAGGRLALLWIVPLTLSGLLGVAWGASSLGAHHIH
Length 60
Organism Homo sapiens (Human)
UniProt ID P58400,
Motif 1..60
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB00705.cif
Physicochemical Information
Molecular weight 5766.66184
Aliphatic index 97.66666667
Isoelectric point 9.502456718
Charge (pH=7) 2.209651631
Topological polar surface area 2267.73
Aromaticity 0.05
Average rotatable bonds 3.083333333
Number of hydrogen bond donors 82
Number of hydrogen bond acceptors 78
X logP energy -25.00509
Hydropathy
Literature Information
Title High frequency of neurexin 1BETA signal peptide structural variants in patients with autism
DOI NA,
Publication Year 2011
PubMed ID NA,
Patent ID US7871820B2,