SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00702

Signal sequence   MQYKKPLVVSALAATSLAAYAPKDPWSTLTPSATYKGGITDYSSSFGIAIEAVATSASSVASSKAKR

Length  67

Organism  Artificial

UniProt ID  NA,

Motif  1..67



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB00702.cif

Structure  SPKB00702.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  6871.81924

Aliphatic index  77.46268657

Isoelectric point  10.10665829

Charge (pH=7)   3.995477219

Topological polar surface area  2782.62

Aromaticity  0.089552239

Average rotatable bonds  3.253731343

Number of hydrogen bond donors  100

Number of hydrogen bond acceptors  102

X logP energy  -33.65813

Hydropathy 



Literature Information


Title  Pichia pastoris PIR1 secretion signal peptide for recombinant protein expression and Pichia pastoris PIR1 and PIR2 anchor domain peptides for recombinant surface display

DOI  NA,

Publication Year  2010

PubMed ID  NA,

Patent ID  US7741075B2,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.