SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00698

Signal sequence   MYRNLIIATALTCGAYSAYVPSEPWSTLTPDASLESALKDYSQTFGIAIKSLDADKIKR

Length  59

Organism  Artificial

UniProt ID  NA,

Motif  1..59



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB00698.cif

Structure  SPKB00698.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  6457.37494

Aliphatic index  91.18644068

Isoelectric point  6.502534512

Charge (pH=7)   -0.063242649

Topological polar surface area  2602.08

Aromaticity  0.101694915

Average rotatable bonds  3.525423729

Number of hydrogen bond donors  93

Number of hydrogen bond acceptors  92

X logP energy  -25.27486

Hydropathy 



Literature Information


Title  Pichia pastoris PIR1 secretion signal peptide for recombinant protein expression and Pichia pastoris PIR1 and PIR2 anchor domain peptides for recombinant surface display

DOI  NA,

Publication Year  2010

PubMed ID  NA,

Patent ID  US7741075B2,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.