SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00586

Signal sequence   MVLWVFFLVILTLSSSSHCSRPPPLPLRMRR

Length  31

Organism  Artificial

UniProt ID  NA,

Motif  1..31



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB00586.cif

Structure  SPKB00586.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3640.47324

Aliphatic index  116.1290323

Isoelectric point  12.50009851

Charge (pH=7)   4.026905429

Topological polar surface area  1314.61

Aromaticity  0.096774194

Average rotatable bonds  3.580645161

Number of hydrogen bond donors  49

Number of hydrogen bond acceptors  46

X logP energy  -7.73562

Hydropathy 



Literature Information


Title  Enhanced secretion/retention of growth hormone releasing hormone (GHRH) from muscle cells by species-specific signal peptide

DOI  NA,

Publication Year  2009

PubMed ID  NA,

Patent ID  US7517863B2,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.