SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00556

Signal sequence   MWLQSLLLLGTVACSIS

Length  17

Organism  Homo sapiens (Human)

UniProt ID  P04141,

Motif  1..17



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  5D71,

Predicted Structure ID  SPKB00556.cif

Structure  SPKB00556.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1835.24994

Aliphatic index  160.5882353

Isoelectric point  5.922539791

Charge (pH=7)   -0.063990417

Topological polar surface area  668.72

Aromaticity  0.058823529

Average rotatable bonds  3.470588235

Number of hydrogen bond donors  25

Number of hydrogen bond acceptors  25

X logP energy  -4.2309

Hydropathy 



Literature Information


Title  Cellular assays for identifying signaling peptides

DOI  NA,

Publication Year  2005

PubMed ID  NA,

Patent ID  US6866998B1,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.