SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00554

Signal sequence   MGSCSGRCALVVLCAFQLVAA

Length  21

Organism  Homo sapiens (Human)

UniProt ID  NA,

Motif  1..21



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB00554.cif

Structure  SPKB00554.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2099.57044

Aliphatic index  116.1904762

Isoelectric point  8.04679067

Charge (pH=7)   0.81205684

Topological polar surface area  790.77

Aromaticity  0.047619048

Average rotatable bonds  3.19047619

Number of hydrogen bond donors  31

Number of hydrogen bond acceptors  30

X logP energy  -8.15843

Hydropathy 



Literature Information


Title  Complementary DNA's encoding proteins with signal peptides

DOI  NA,

Publication Year  2003

PubMed ID  NA,

Patent ID  US6548633B1,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.