SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00553

Signal sequence   MLSPTFVLWDVGYPLYTYGSICIIALIIWQVKKSCQKLSLVPNRSCCRCHRRVQQKSGDRTSRASQEEAEKLWKLLFRRTLMKSQG

Length  86

Organism  Homo sapiens (Human)

UniProt ID  NA,

Motif  1..86



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB00553.cif

Structure  SPKB00553.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  10036.85904

Aliphatic index  88.37209302

Isoelectric point  10.40450945

Charge (pH=7)   9.780595177

Topological polar surface area  4075.65

Aromaticity  0.093023256

Average rotatable bonds  3.930232558

Number of hydrogen bond donors  152

Number of hydrogen bond acceptors  138

X logP energy  -37.21974

Hydropathy 



Literature Information


Title  Complementary DNA's encoding proteins with signal peptides

DOI  NA,

Publication Year  2003

PubMed ID  NA,

Patent ID  US6548633B1,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.