SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00552

Signal sequence   MDNVQPKIKHRPFCFSVKGHVKMLRLALTVTSMTFFIIAQAPEPYIVITGFEVTVILFFILLYVLRLDRLMKWLFWPLLDIINSLVTTVFMLIVSVLALIP

Length  101

Organism  Homo sapiens (Human)

UniProt ID  NA,

Motif  1..101



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB00552.cif

Structure  SPKB00552.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  11710.41604

Aliphatic index  142.6732673

Isoelectric point  10.16967696

Charge (pH=7)   4.11952822

Topological polar surface area  4009.07

Aromaticity  0.128712871

Average rotatable bonds  3.722772277

Number of hydrogen bond donors  140

Number of hydrogen bond acceptors  141

X logP energy  -9.70122

Hydropathy 



Literature Information


Title  Complementary DNA's encoding proteins with signal peptides

DOI  NA,

Publication Year  2003

PubMed ID  NA,

Patent ID  US6548633B1,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.