SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00550

Signal sequence   MNQENPPPYPGPGPTAPYPPYPPQPMGPGPMGGPYPPPQGYPYQGYLQYGWQGGPQEPPKTTVYVVEDQRRDELGPSTCLTACWTALCCC

Length  90

Organism  Homo sapiens (Human)

UniProt ID  NA,

Motif  1..90



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB00550.cif

Structure  SPKB00550.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  9784.02644

Aliphatic index  30.33333333

Isoelectric point  4.103602562

Charge (pH=7)   -3.311851205

Topological polar surface area  3610.83

Aromaticity  0.122222222

Average rotatable bonds  2.955555556

Number of hydrogen bond donors  114

Number of hydrogen bond acceptors  134

X logP energy  -34.91596

Hydropathy 



Literature Information


Title  Complementary DNA's encoding proteins with signal peptides

DOI  NA,

Publication Year  2003

PubMed ID  NA,

Patent ID  US6548633B1,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.