SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00549

Signal sequence   MNQENPPPYPGPGPTAPYPPYPPQPMGPGPMGGPYPPPQGYPYQGYLQYGWHGGPQEPPKTTVYVVEDQRRDELGPSTCLTACWTALCCC

Length  90

Organism  Homo sapiens (Human)

UniProt ID  NA,

Motif  1..90



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB00549.cif

Structure  SPKB00549.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  9793.03684

Aliphatic index  30.33333333

Isoelectric point  4.382654473

Charge (pH=7)   -3.220942114

Topological polar surface area  3596.42

Aromaticity  0.122222222

Average rotatable bonds  2.944444444

Number of hydrogen bond donors  114

Number of hydrogen bond acceptors  134

X logP energy  -34.21566

Hydropathy 



Literature Information


Title  Complementary DNA's encoding proteins with signal peptides

DOI  NA,

Publication Year  2003

PubMed ID  NA,

Patent ID  US6548633B1,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.