SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00548

Signal sequence   MERPRSPQCSAPASASASVTLAQLLQLVQQ

Length  30

Organism  Homo sapiens (Human)

UniProt ID  NA,

Motif  1..30



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB00548.cif

Structure  SPKB00548.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3168.63364

Aliphatic index  88

Isoelectric point  8.549845238

Charge (pH=7)   0.937778084

Topological polar surface area  1378.78

Aromaticity  0

Average rotatable bonds  3.4

Number of hydrogen bond donors  47

Number of hydrogen bond acceptors  47

X logP energy  -18.68396

Hydropathy 



Literature Information


Title  Complementary DNA's encoding proteins with signal peptides

DOI  NA,

Publication Year  2003

PubMed ID  NA,

Patent ID  US6548633B1,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.