SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00546

Signal sequence   MTDLDLMINFTFPIQWVNQNRMAYYSLKPLLPCSSVLTCGQA

Length  42

Organism  Homo sapiens (Human)

UniProt ID  NA,

Motif  1..42



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB00546.cif

Structure  SPKB00546.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  4824.68124

Aliphatic index  92.85714286

Isoelectric point  6.171571601

Charge (pH=7)   -0.127071338

Topological polar surface area  1828.74

Aromaticity  0.119047619

Average rotatable bonds  3.619047619

Number of hydrogen bond donors  63

Number of hydrogen bond acceptors  66

X logP energy  -14.74573

Hydropathy 



Literature Information


Title  Complementary DNA's encoding proteins with signal peptides

DOI  NA,

Publication Year  2003

PubMed ID  NA,

Patent ID  US6548633B1,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.