SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00545

Signal sequence   MSFLRITPSTHSSVSSGLLRLSIFLLLSFPDSNG

Length  34

Organism  Homo sapiens (Human)

UniProt ID  NA,

Motif  1..34



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB00545.cif

Structure  SPKB00545.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3681.26454

Aliphatic index  111.7647059

Isoelectric point  10.39953455

Charge (pH=7)   1.089333252

Topological polar surface area  1461.44

Aromaticity  0.088235294

Average rotatable bonds  3.470588235

Number of hydrogen bond donors  53

Number of hydrogen bond acceptors  52

X logP energy  -16.24126

Hydropathy 



Literature Information


Title  Complementary DNA's encoding proteins with signal peptides

DOI  NA,

Publication Year  2003

PubMed ID  NA,

Patent ID  US6548633B1,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.