SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00544

Signal sequence   MDKVQSGFLILFLFLMECQL

Length  20

Organism  Homo sapiens (Human)

UniProt ID  NA,

Motif  1..20



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB00544.cif

Structure  SPKB00544.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2375.92774

Aliphatic index  131.5

Isoelectric point  4.184374539

Charge (pH=7)   -1.062063843

Topological polar surface area  823.25

Aromaticity  0.15

Average rotatable bonds  4.05

Number of hydrogen bond donors  28

Number of hydrogen bond acceptors  30

X logP energy  -1.6706

Hydropathy 



Literature Information


Title  Complementary DNA's encoding proteins with signal peptides

DOI  NA,

Publication Year  2003

PubMed ID  NA,

Patent ID  US6548633B1,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.