SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00542

Signal sequence   MKGGISNVWFDRFKITNDCPEHLESIDVMCQVLTDLIDEEVKSGIKKNRILIGGFSMGGCMAMHLAYRNHQDVAGVFALSSFLNKASA

Length  88

Organism  Homo sapiens (Human)

UniProt ID  NA,

Motif  1..88



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  3U0V,

Predicted Structure ID  SPKB00542.cif

Structure  SPKB00542.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  9722.26074

Aliphatic index  88.63636364

Isoelectric point  6.767192061

Charge (pH=7)   -0.908063731

Topological polar surface area  3906.81

Aromaticity  0.079545455

Average rotatable bonds  3.761363636

Number of hydrogen bond donors  137

Number of hydrogen bond acceptors  136

X logP energy  -37.34089

Hydropathy 



Literature Information


Title  Complementary DNA's encoding proteins with signal peptides

DOI  NA,

Publication Year  2003

PubMed ID  NA,

Patent ID  US6548633B1,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.