SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00541

Signal sequence   MVCEDAPSFQMAWESQMAWERGPALLCCVLSASQLSS

Length  37

Organism  Homo sapiens (Human)

UniProt ID  NA,

Motif  1..37



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB00541.cif

Structure  SPKB00541.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  4063.67844

Aliphatic index  71.35135135

Isoelectric point  3.778217515

Charge (pH=7)   -3.182171307

Topological polar surface area  1586.67

Aromaticity  0.081081081

Average rotatable bonds  3.486486486

Number of hydrogen bond donors  57

Number of hydrogen bond acceptors  58

X logP energy  -16.08713

Hydropathy 



Literature Information


Title  Complementary DNA's encoding proteins with signal peptides

DOI  NA,

Publication Year  2003

PubMed ID  NA,

Patent ID  US6548633B1,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.