SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00540

Signal sequence   MYFHFLGAGAILIPRLDIVISFVGAVSS

Length  28

Organism  Homo sapiens (Human)

UniProt ID  NA,

Motif  1..28



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB00540.cif

Structure  SPKB00540.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2994.58784

Aliphatic index  139.2857143

Isoelectric point  7.542962956

Charge (pH=7)   0.088486149

Topological polar surface area  1049.03

Aromaticity  0.142857143

Average rotatable bonds  3.321428571

Number of hydrogen bond donors  37

Number of hydrogen bond acceptors  37

X logP energy  -4.65113

Hydropathy 



Literature Information


Title  Complementary DNA's encoding proteins with signal peptides

DOI  NA,

Publication Year  2003

PubMed ID  NA,

Patent ID  US6548633B1,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.