SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00539

Signal sequence   MNKTHKDCSSPQYSIYNILNELPTRPIILSCSQISCLLLVSTWSADLMS

Length  49

Organism  Homo sapiens (Human)

UniProt ID  NA,

Motif  1..49



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB00539.cif

Structure  SPKB00539.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  5516.41774

Aliphatic index  103.4693878

Isoelectric point  7.177816981

Charge (pH=7)   -0.096656874

Topological polar surface area  2202.73

Aromaticity  0.06122449

Average rotatable bonds  3.653061224

Number of hydrogen bond donors  79

Number of hydrogen bond acceptors  81

X logP energy  -23.13583

Hydropathy 



Literature Information


Title  Complementary DNA's encoding proteins with signal peptides

DOI  NA,

Publication Year  2003

PubMed ID  NA,

Patent ID  US6548633B1,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.