SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00538

Signal sequence   MNLMWTLLLFLLLDVTVFIPALP

Length  23

Organism  Homo sapiens (Human)

UniProt ID  NA,

Motif  1..23



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB00538.cif

Structure  SPKB00538.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2674.38144

Aliphatic index  182.173913

Isoelectric point  3.749987361

Charge (pH=7)   -1.001569216

Topological polar surface area  822.58

Aromaticity  0.130434783

Average rotatable bonds  3.52173913

Number of hydrogen bond donors  27

Number of hydrogen bond acceptors  30

X logP energy  2.6504

Hydropathy 



Literature Information


Title  Complementary DNA's encoding proteins with signal peptides

DOI  NA,

Publication Year  2003

PubMed ID  NA,

Patent ID  US6548633B1,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.