SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00537

Signal sequence   MWTFSYIGFPVELNTVYFIGAHKIPNANMNEDGPSMSVNFTSPGCLDHIMKYKKKCVKAGSLWDPNITACKKNEETVEVNFTTTPLGNRYMALIQHSTIIGFSQVFEPHQKKQTRASVVIPVTGDSEGATVQLTPYFPTCGSDCIRHKGTVVLCPQTGVPFPLDNNKSKPGGWLPLLLLSLLVA

Length  184

Organism  Homo sapiens (Human)

UniProt ID  NA,

Motif  1..184



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB00537.cif

Structure  SPKB00537.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  20233.41894

Aliphatic index  80.97826087

Isoelectric point  8.370563426

Charge (pH=7)   3.087688777

Topological polar surface area  7856.52

Aromaticity  0.092391304

Average rotatable bonds  3.516304348

Number of hydrogen bond donors  269

Number of hydrogen bond acceptors  280

X logP energy  -90.07349

Hydropathy 



Literature Information


Title  Complementary DNA's encoding proteins with signal peptides

DOI  NA,

Publication Year  2003

PubMed ID  NA,

Patent ID  US6548633B1,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.