SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00536

Signal sequence   MESGGRPSLCQFILLGTTSVVTA

Length  23

Organism  Homo sapiens (Human)

UniProt ID  NA,

Motif  1..23



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB00536.cif

Structure  SPKB00536.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2367.76084

Aliphatic index  97.39130435

Isoelectric point  6.232433001

Charge (pH=7)   -0.062218605

Topological polar surface area  958.4

Aromaticity  0.043478261

Average rotatable bonds  3.304347826

Number of hydrogen bond donors  35

Number of hydrogen bond acceptors  35

X logP energy  -11.58093

Hydropathy 



Literature Information


Title  Complementary DNA's encoding proteins with signal peptides

DOI  NA,

Publication Year  2003

PubMed ID  NA,

Patent ID  US6548633B1,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.