SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00535

Signal sequence   MEAGGFLDSLIYGACVVFTLGMFSAGLS

Length  28

Organism  Homo sapiens (Human)

UniProt ID  NA,

Motif  1..28



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB00535.cif

Structure  SPKB00535.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2857.34694

Aliphatic index  101.0714286

Isoelectric point  3.550065682

Charge (pH=7)   -2.062619224

Topological polar surface area  1024.77

Aromaticity  0.142857143

Average rotatable bonds  3.25

Number of hydrogen bond donors  37

Number of hydrogen bond acceptors  39

X logP energy  -7.9433

Hydropathy 



Literature Information


Title  Complementary DNA's encoding proteins with signal peptides

DOI  NA,

Publication Year  2003

PubMed ID  NA,

Patent ID  US6548633B1,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.