SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00534

Signal sequence   MDRRATSFPPLPAKERRAGISSALPCPPTMSLSDSLWSPHCSWS

Length  44

Organism  Homo sapiens (Human)

UniProt ID  NA,

Motif  1..44



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB00534.cif

Structure  SPKB00534.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  4828.53394

Aliphatic index  53.40909091

Isoelectric point  8.830772036

Charge (pH=7)   1.96730377

Topological polar surface area  1921.4

Aromaticity  0.068181818

Average rotatable bonds  3.272727273

Number of hydrogen bond donors  70

Number of hydrogen bond acceptors  69

X logP energy  -22.55952

Hydropathy 



Literature Information


Title  Complementary DNA's encoding proteins with signal peptides

DOI  NA,

Publication Year  2003

PubMed ID  NA,

Patent ID  US6548633B1,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.