SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00533

Signal sequence   MDKSLLLELPILLCCFRALSGSLS

Length  24

Organism  Homo sapiens (Human)

UniProt ID  NA,

Motif  1..24



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB00533.cif

Structure  SPKB00533.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2623.22254

Aliphatic index  150.4166667

Isoelectric point  6.220978782

Charge (pH=7)   -0.124041871

Topological polar surface area  967.27

Aromaticity  0.041666667

Average rotatable bonds  3.666666667

Number of hydrogen bond donors  36

Number of hydrogen bond acceptors  36

X logP energy  -6.32253

Hydropathy 



Literature Information


Title  Complementary DNA's encoding proteins with signal peptides

DOI  NA,

Publication Year  2003

PubMed ID  NA,

Patent ID  US6548633B1,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.