SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB00532

Signal sequence   MAHRLQIRLLTWDVKDTLLRLRHPLGEAYATKARAHGLEVEPSALEQGFRQAYRAQSHSFPNYGLSHGLTSRQWWLDVVLQTFHLAGVQDAQAVAPIAEQLYKDFSHPCTWQVLDGAEDTLRECRTRGLRLAVISNFDRRLEGILEGLGLREHFDFVLTSEAAGWPKPDPRIFQEALRLAHMEPVVAAHVGDNYLCDYQGPRAVGMHSFLVVGPQALDPVVRDSVPKEHILPSLAHLLPALDC

Length  243

Organism  Homo sapiens (Human)

UniProt ID  NA,

Motif  1..243



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Artificial

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB00532.cif

Structure  SPKB00532.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  27317.20324

Aliphatic index  95.96707819

Isoelectric point  6.701507929

Charge (pH=7)   -4.043187971

Topological polar surface area  11028.78

Aromaticity  0.082304527

Average rotatable bonds  3.621399177

Number of hydrogen bond donors  384

Number of hydrogen bond acceptors  359

X logP energy  -154.27517

Hydropathy 



Literature Information


Title  Complementary DNA's encoding proteins with signal peptides

DOI  NA,

Publication Year  2003

PubMed ID  NA,

Patent ID  US6548633B1,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.